Tuesday, 29 November 2022


Takeda focuses on potential new therapies for COVID-19

28 May 2020 | News

'The Fight Is In Us' Campaign Seeks to Mobilize COVID-19 Survivors to Accelerate the Development of Potentially Lifesaving Therapies

Image credit- shutterstock.com

Image credit- shutterstock.com

Japanese firm Takeda Pharmaceutical Company Limited is a key leader of a coalition who has announced that world-leading medical and research institutions, blood centers, life science companies, technology companies, philanthropic organizations, and COVID-19 survivor groups have come together to support the rapid development of potential new therapies for patients with COVID-19.

Working together under the “The Fight Is In Us” campaign, the coalition is seeking to mobilize tens of thousands of people in the United States who have recovered from COVID-19 to donate their blood plasma, which contains vital antibodies that have fought off the disease and could now help others do the same.

The campaign is working against two urgent timelines: to recruit COVID-19 survivors within two months of their recovery to ensure that their blood plasma contains a robust enough concentration of antibodies to have a positive effect, and to address the substantial seasonal increase in COVID-19 cases anticipated this fall in the Northern Hemisphere by the Centers for Disease Control and Prevention (CDC) and other public health experts.

The coalition partners are working on two distinct approaches for treating COVID-19 that both urgently require collection of convalescent plasma now. One approach is the direct transfusion of blood plasma though the Expanded Access Program for convalescent plasma, which is currently being administered with authorization from the Food & Drug Administration by Mayo Clinic. Its safety and efficacy are currently being evaluated through multiple clinical trials in different populations.

Blood donor centers throughout the country are currently collecting convalescent plasma from COVID-19 survivors for this purpose. The other approach is the development of a medicine known as a hyperimmune globulin (H-Ig), which is being manufactured now and will be studied in clinical trials this summer.

Through the manufacturing process, the plasma is pooled, concentrated and purified, resulting in a vial of medicine with consistent levels of antibodies that is easy to store, distribute and administer to patients. Coalition members developing an H-Ig include the CoVIg-19 Plasma Alliance (CSL Behring, Takeda, ADMA Biologics, Biopharma Plasma, Biotest, BPL, GC Pharma, LFB, Octapharma and Sanquin) and Grifols.

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