Saturday, 04 July 2020


Researchers design a paper based test for Tuberculosis

14 September 2017 | News

A diagnostic test is being designed that can be read with a smartphone.

Courtesy- Tuiris

Courtesy- Tuiris

Conventional methods such as sputum smear microscopy, chest X-rays and molecular-based tests require equipment, electricity and specialized personnel that are not always available in remote or developing areas.

So a group of scientists from National Taiwan University are set to come up with a more practical diagnostic test that can be read with a smartphone, a technology that is increasingly available in emerging economies.

The researchers combined gold nanoparticles with fluorescent single-stranded DNA sequences that bind to the genetic material of Mycobacterium tuberculosis or Mtb, the bacteria that cause TB.

These nanoparticles were then incorporated into a paper-based device. Adding even a minute amount of lab-derived, double-stranded DNA from Mtb changed the color of the test spots within an hour. A smartphone camera was used to analyze the color change to determine the bacterial concentration.

The researchers also tested a tissue sample from an infected patient to further demonstrate that the device could be used in the field.


Sign up for the editor pick and get articles like this delivered right to your inbox.

Editors Pick
+Country Code-Phone Number(xxx-xxxxxxx)


Comments

× Your session has been expired. Please click here to Sign-in or Sign-up
   New User? Create Account