22 November 2019 | News
Initiation of a Phase 2 Multicenter Study of 18F-APN-1607
image credit- medicalnewstoday.com
Taiwan based APRINOIA Therapeutics, Inc. has announced that it has initiated a Phase 2 multicenter, multinational study of 18F-APN-1607 in the US for its lead tau positron emission tomography (PET) tracer in Alzheimer's Disease (AD). The study (NCT number: NCT04141150) will compare tau deposition patterns in patients with mild cognitive impairment due to AD and dementia due to AD with patterns in healthy older adults.
In addition to the Phase 2 study in AD, APRINOIA is establishing a clinical research network with leading imaging centers worldwide to conduct medical research with 18F-APN-1607. Such research includes clinical/imaging correlation studies, investigation of longitudinal tau pathology progression and spread in individual tauopathies, exploration of potential utilities in differential diagnosis, and studies to develop new AI-based tau PET image analytical tools.