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Kyowa Hakko Kirin to return rights of Busulfex

17 September 2012 | News | By BioSpectrum Bureau

Kyowa Hakko Kirin to return rights of Busulfex to Otsuka

Kyowa Hakko Kirin will return development and marketing rights of Busulfex to Otsuka

Kyowa Hakko Kirin will return development and marketing rights of Busulfex to Otsuka

Singapore: Kyowa Hakko Kirin has agreed to return development and marketing rights of Busulfex, for use as a part of conditioning regimen prior to hematopoietic progenitor cell transplantation, to its original licensor Otsuka Pharmaceutical. Busulfex is currently developed and marketed by Kyowa Hakko Kirin in Japan and in six Asian countries and regions (China, Korea, Taiwan, Singapore, Malaysia and Thailand).

Otsuka Pharmaceutical is the distributor and the original licensor of all global businesses encircling Busulfex. Kyowa Hakko Kirin had licensed-in the development rights and dealership within Japan and in Asian countries and regions. The contract will terminate as of March 31, 2013, and Kyowa Hakko Kirin will return the rights to Otsuka Pharmaceutical from April 1, 2013. Kyowa Hakko Kirin will receive $26.7 million (JPY 2.1 billion) in accordance with the returning of Busulfex.

Busulfex is currently sold in 57 countries and regions, and has now become established as the standard drug as a conditioning agent administered prior to bone marrow transplants, an important treatment together with radiotherapy. Busulfex will be developed and marketed in nine countries and regions including the US and Canada, once its development and marketing rights within Japan and in Asian countries and regions are returned to Otsuka Pharmaceutical.

Otsuka Pharmaceutical has been conducting the global business encircling Busulfex since March 2008. Busulfex is marketed by Otsuka Pharmaceutical's local affiliate in the US and in Canada, and Kyowa Hakko Kirin and its local affiliates market Busulfex in Asian countries and regions including Japan. Laboratoire Pierre Fabre markets Busulfex in Europe, Latin America and Africa.

Upon the returning of Busulfex from Kyowa Hakko Kirin to Otsuka Pharmaceutical, both companies will take all possible measures to ensure the fluent transfer of business operations, including product distribution and product communications.

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