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Korea-US partnership to co-develop therapy for Parkinson's Disease

26 May 2023 | News

HanAll Biopharma and Daewoong Pharmaceutical enter into co-development agreement with NurrOn Pharmaceuticals

Image credit: shutterstock

Image credit: shutterstock

South Korean firms HanAll Biopharma and Daewoong Pharmaceutical have entered into a co-development agreement with NurrOn Pharmaceuticals Inc., a US-based preclinical-stage biopharma firm.

NurrOn is focused on the discovering and developing novel therapies for people with neurodegenerative diseases including Parkinson's disease (PD) by targeting Nurr1, the master regulator for dopaminergic neuron development and maintenance. HanAll and Daewoong also participated in a Series A funding of NurrOn in 2021.

NurrOn was founded by Kwang-Soo Kim, Ph.D., Professor and Director of the molecular neurobiology laboratory at Harvard Medical School, and Deog Joong Kim, Ph.D. and was seed-funded by George A. Lopez, M.D., former CEO of ICU Medical, Inc. Using the technology, NurrOn is advancing the development of its lead compound ATH-399A, which potentially slows the progression of the disease in PD patients by activating Nurr1, a class of proteins crucial to the development and maintenance of dopamine in the brain.

Under the agreement, the companies will combine their expertise and resources in developing NurrOn's ATH-399A as well as other compounds targeting Nurr1 for the treatment of neurodegenerative disorders.

In addition to proceeding towards a Phase 1 trial of its Parkinson's therapy candidate ATH-399A, the partners will continue to explore the potential of ATH-399A in other neurodegenerative diseases.

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