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Topic

Exploring CHO cell culture medium stability risks and trace elements variance in cell culture performance.

Synopsis

CD (chemically defined) CHO cell culture medium is widely used in biopharmaceutical. It can greatly influence cell culture, such as cell growth, metabolism, titer and CQA (critical quality attributes). The webinar presents analysis of CHO cell culture medium stability risk and mainly focuses on key raw material variance---TE (trace element). Deep knowledge of TE variance in cell culture is provided. Some effective strategies should be taken in controlling variance so as to realize high performance and high quality CHO cell culture medium product.

Speaker

Yiming Yang

Yiming Yang

CCM technical manager, Duoning Biotech

The Presenters Will Discuss

Brief introduction of DUONING Biotech
CCM stability risk analysis. It includes raw material, precipitate, degradation and manufacturing process.
Issues that cause TE variance.
TE variance influence in cell growth, metabolism, titer and CQA.
Some strategies that control variance and stability.

Key Learning Objectives

Understand the importance of CHO cell culture medium stability.
Knowledge of TE variance influence in cell culture.
How to design and develop CCM formula to control stability.

Speaker Details

Yiming Yang is highly experienced in cell culture medium development. He previously worked in R＆D department and led many customized medium development projects. In R＆D department, he was responsible for CHO cell culture medium formula development and succeed to develop WUXI biologics platform medium, Highpro series. Now, he is responsible for CCM promotion of Chines and oversea market, supported over 15 commercialization projects. He has accomplished Bioprocess engineering postgraduate in DCU (Dublin City University) and NIBRT (National institute for bioprocessing research and training) in Dublin, Ireland. He also possesses deep knowledge of upstream bioprocess and antibody industry market.

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