Have a look at AstraZeneca's development pipeline

Singapore: AstraZeneca (AZ) revealed that during its fourth quarter and the full year of 2012, its revenue declined 15 percent at constant exchange rates (CER) to $27,973 million. The financial report reflected the loss of exclusivity on several AZ brands. The company will hold a Capital Markets Day on March 21, 2013, to provide a strategy update. AstraZeneca also unveiled the status of its developmental pipeline for the year ending December 31, 2012. Click here to view AstraZeneca's development pipeline in .PDF format.

Brilinta/Brilique, Symbicort, Faslodex, Onglyza and Iressa continued to grow, while diabetes alliance franchise strengthened by the inclusion of Amylin portfolio and the approval of Forxiga in Europe. Loss of exclusivity on several brands and the disposals of Astra Tech and Aptium were the key drivers of the revenue decline. Symbicort, Faslodex, Onglyza, Iressa, Brilinta/Brilique and Seroquel XR combined to deliver $600 million of CER revenue growth for the full year. Core EPS was $6.41 for the full year, a nine percent decline at CER.

Core EPS in 2012 benefited by $470 million ($0.37) from two separate tax related matters during the year. Proceeds from the sale of Nexium OTC rights contributed $0.16 to Core EPS. Reported EPS for the full year was down 29 percent at CER to $4.99. The decline reflects the $1.08 per
share benefit in 2011 from the sale of Astra Tech and higher restructuring costs in 2012. Revenue in the fourth quarter was down 15 percent. Core EPS was up one percent as a result of lower operating costs (including significantly lower intangible impairment costs in R&D) and a favourable
$230 million adjustment to deferred tax balances following substantive enactment of a reduction in the Swedish corporation tax rate.

The board declared a second interim dividend of $1.90 per share, bringing the dividend for the full year to $2.80, consistent with the progressive dividend policy. The company expects a mid-to-high single digit percentage decline in revenue at CER for 2013. With core operating costs expected to be slightly higher than 2012 at CER, core EPS will decline significantly more than revenue.

Dr Pascal Soriot, CEO, AstraZeneca, while commenting on the results, said that, "Our performance in 2012 reflects a period of significant patent expiry and tough market conditions globally. Despite the challenges we face, I am excited about AstraZeneca's fundamental strengths which will be key in returning the company to growth and achieving scientific leadership while maintaining our reputation for strong financial discipline."