Singapore, Aug 25, 2010: EMD Millipore, the life sciences division of Merck, Germany, has introduced the first software application for visualizing GPCR (G-protein coupled receptors), as well as kinase activity. The new data analysis and report tool (DART), which can be accessed through EMD Millipore's drug discovery portal, creates an interactive map of target profiling assay results and enables drug researchers to make faster and more informed decisions.
"Lead profiling often requires sifting through hundreds or even thousands of data points to pinpoint targets for further optimization studies. This new online tool provides a unique, information-rich interface so scientists can rapidly narrow their research and effectively collaborate with colleagues," said Paul Wilhite, senior manager of eBusiness at EMD Millipore.
The application projects each compound's activity profile onto a map depicting clusters of target protein families. This map provides scientists with immediate graphical insight into cross-target interactions to help drive structure-activity relationship (SAR) studies. The application is fully-customizable. Data limits, sizing, colors, and target sub-classes can be adjusted in seconds, thereby turning numerical data into a graphical display that can highlight biologically significant conclusions. Additionally, selected target information is dynamically populated and includes the gene symbol and aliases; links to bioinformatics content and recent publications; as well as links to appropriate EMD Millipore products.
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