Singapore, Jul 2, 2009: Studies have shown it is a normal progression for ageing men to suffer from enlarged prostate. At least 50 percent of men above 50 years will suffer from this condition. But, by not seeking early diagnosis and treatment, they may run the risk of developing acute urinary retention or reach a stage where they may need prostate-related surgery eventually.

 

As men increase in age, their risk of developing prostate cancer increases. Studies have shown that men with a single first-degree relative (father, brother or son) with a history of prostate cancer are twice as likely to develop the disease. The risk is highest in men whose family members were diagnosed before age 65.

 

Dr Michael Wong, President of the Singapore Urological Association (SUA) said “Although it is part of the natural ageing process, prostate enlargement is a treatable condition. Scientific advances and new drugs have made it possible today for men to avoid surgery and to enjoy a really good quality of life in their golden years rather than suffer in silence and be resigned to this condition. ”

 

Dr Wong also noted that Avodart, a drug from GlaxoSmithKline, reduces the risk of prostate cancer. The results of the REDUCE trial study found that Avodart, known generically as dutasteride, significantly reduced the risk of all biopsy-detectable prostate cancer by 23 percent over four years, compared against those who took a placebo.

The trial looked at men who were at increased risk for prostate cancer because they had raised levels of prostate-specific antigen. The study found no statistically significant difference in the incidence of high-grade tumors, which had been a problem seen in an earlier trial with other drug, Proscar.”

 

Dr Ng Chee Kwan, consultant Urologist at Tan Tock Seng Hospital said “A recent randomized study from Europe underscores the importance of seeing a doctor for prostate health check, as it shows screening for prostate cancer reduces the rate of death from prostate cancer by 20 percent. At the same time, screening for prostate cancer carries the risk of over treatment of the disease. However, with more knowledge of the available treatment options, patients can make an informed decision of how to proceed.

 

Referring to a recent study involving almost 1,000 Asian men between 48–88 years old, Dr Kwan said, medication and surgery resulted in greater reduction of lower urinary tract symptoms and an improvement in sexual function compared with watchful waiting (where no surgery or other treatment takes place).