Updated on 12 April 2012
Numerous corporate developments and research initiatives are being undertaken globally to improve targeted drug delivery, which involves delivery of drug to specific sites on disease infected cells, thereby controlling the dosage and improving the pharmacological properties.
Targeted drug delivery aims at achieving high, local concentrations of drugs, and the possibility to track the drug's action at a target site. Since the drug is delivered to the target site, this method of drug delivery does not cause damage to normal tissues and helps prevent drug resistance and metastasis, which is quite common in disease indications.
The market for new targeted delivery technologies is growing at a rapid pace as pharmaceutical companies are realizing the importance of effective formulation and delivery strategies to reduce the side effects of drugs, lower the dosage, and work on cost effectiveness and safety reasons.
Generic products that face commoditization and increasing competition can create a niche in the market by differentiating themselves based on the delivery mode and can help create a unique patenting strategy. Some of the main advantages of using targeted delivery systems are improvement of drug solubility, reduced systemic toxicity, better bioavailability, and ability to target specific receptors and act on specific pathways, simultaneous imaging, and targeting.