Updated on 13 May 2013
Dr Krishna Ella, chairman and managing director, Bharat Biotech, and member of the Scientific Advisory Committee to the Prime Minister, India
My journey as a scientist and a entrepreneur began with my strong interest in science and how it relates to health and wellness. I am very much concerned about public health, especially neglected and preventable diseases that affect human life. I knew I could only make a difference as an entrepreneur. I founded Bharat Biotech in 1996 along with my wife Suchitra with a vision to create a truly Indian multinational company. The primary focus was to develop and produce world class vaccines and biopharmaceuticals that are safe and affordable to every section of the society.
Today, our company is located in Genome Valley, Hyderabad, which is one of Asia's largest biotech facilities that helps catalyze growth of life sciences companies. With more than 100 companies engaged in life sciences research, product development and manufacturing, we are proud that Genome Valley in Hyderabad is growing rapidly. With over 2.5 billion doses delivered worldwide, Bharat Biotech is globally recognized for its innovative research, good manufacturing practices and highly motivated talent pool of scientists and researchers. We delivered the world's first cesium-free hepatitis vaccine, Revac-B, developed indigenously using our patented Himax technology that costs less than a bottle of water.
I grew up in an agricultural family. As a young man, I wanted to study agricultural sciences and become a farmer. After my studies, I decided to work in a large multinational company. Although I was interested in research at that time, I was not happy with the kind of research that was being conducted in India. My interest to pursue science intensified when I traveled to the US with the help of Rotary Foundation Scholarship, to study molecular biology at the Universities of Hawaii and Wisconsin-Madison. The thought-provoking lectures from National Science Academy winners and Nobel Laureates led to a paradigm shift of my thought process. I decided to challenge all the risks and to pursue science passionately. Afterwards, I successfully completed my master's degree from the University of Hawaii, got a doctorate from the University of Wisconsin-Madison and then chose to move to the Medical University of South Carolina-Charleston for further research and teaching.
It was during this period in the US, that I took the first step towards nurturing my entrepreneurial dreams. It was a difficult choice and although I was not keen to return to India, I got strong support from my wife and my mother to take the first step. My biggest inspiration came from my mother who said, "Son, you only have a nine-inch stomach and how much ever money you make, you can't eat more than that. You come back and do whatever you want; I will see to it that you get food! As long as I am alive, you will not starve."
I decided to move back to India in 1996 with a 40-feet container, in order to pursue my ambition to establish a hepatitis vaccine business and started conceptualizing an affordable vaccine for hepatitis prevention, which had a big demand in India. I began by setting up a small lab in Hyderabad with the research equipment I had brought along with me from the US and started producing the protein. Initially, I had to face stiff resistance from financial institutions and investors, who thought my idea lacked business foresight. Especially, my proposed price for the vaccine was $1, when the going rate was $35-to-$40. I was looked at with suspicion as the proposed cost of my project and the price of the vaccine was so much less, compared to other proposals they received. However, this did not deter my spirit as I believed that science and business are very similar. In both the domains, you plan and implement ideas. If it is hypothesis in science, it is business plan in commerce. If its risk analysis in business, its testing the methods in science.