Updated on 2 May 2012
It is expanding partnerships along defined paths that include integration of early-stage ADMET screening labs, application to different cell culture models for multiple target organ toxicities and addressing drug withdrawals from the market due to safety problems.
SimuGen does not rely on traditional hazard identification methods such as ‘gene expression signatures', but explicitly models how genes are expressed with increasing toxicity over a wide spectrum of safety concerns. This means risk assessment of clinical endpoints such as fatty liver, zone 3 necrosis or carcinogenesis, within a framework of the drug safety priorities, is now made possible.
While operating in Malaysia, SimuGen also has an office in London to retain close relationships with Europe's leading bioscience and technology pools.
SimuGen has evolved over the last few years into a company at the forefront of early stage toxicology screening services and products.
"The four-stage HT-X screening program is a testament of our capability to translate real customer needs into a fully integrated service that allows customers to make data-rich decisions on compounds in early development. We will continue to innovate and commercialize additional safety screening services and products in the coming period that will contribute to the company's vision to become the leading predictive toxicology player in the industry," says Mr Matthijs van Leeuwen.