PGASO is superior to current technologies for genome engineering for four reasons; multiple genes can be transformed into a genome in one single step; specific upstream promoter sequences are employed for gene assembly in a pre-designed order without linker sequence; gene cassettes with individual promoters can be co-expressed with different expression levels; and PGASO is applicable to any host whose genome can be engineered via homologous recombination, said first author Dr Jui-Jen Chang.

Synthetic biology is a field of translational research that combines science and engineering. Recently, it has been dubbed the source of a possible "biological" industrial revolution. It is expected to be an upcoming key area in the commercialization of research, with close ties between academics and industry.