Updated on 4 January 2017
Prof Uday Maitra and his students at IISc recently fabricated a paper that detects the presence of lipase.
The development of user-friendly biosensors, which plays an important role in the field of biological and medical sciences and in the diagnosis of different diseases, especially in resource limited areas is the overall aim of the project. Biosensors are devices that can be used to detect biological elements like tissues, microorganisms and enzymes by measuring the interaction of a chemical substance with the biological element.
The research team, comprising Prof Uday Maitra and his student Tumpa Gorai from the Indian Institute of Science (IISc), Bengaluru said, "This first-of-its-kind sensor can be envisaged as a portable and disposable analytical device.Enzymes are one of the important target of bioanalytes in the field of biosensors as they play crucial roles in the regulation of metabolic functions in living systems. The detection of enzyme activity through an efficient and simple design is, therefore, of utmost importance. Our lab has fabricated a low-cost paper biosensor that rapidly detects the presence of lipase, a pancreatic enzyme, which breaks down fats into smaller molecules called fatty acids and glycerol during the process of digestion. While a certain amount of lipase is important for maintaining normal digestive function, an abnormally high level of lipase indicates damage to the pancreas.
They also added, "The paper-based sensor is inexpensive, user-friendly and needs low volumes of biological sample for analysis. This strategy has the potential to be useful for possible clinical applications,"