Updated on 16 May 2015
The findings may lead to recommendations for use of antibiotics and a clinical test for measuring the development of gut microbe in children
Singapore: According to researchers at the University of Minnesota, common prescribed antibiotics have indicated changes in the gut bacteria which may cause obesity in young children later in life. This may also cause Dysbiosis, an imbalance in gut microbes, including other vulnerable infectious diseases, allergies and autoimmune disorders.
One of the graduate student fellows from Biomedical Informatics and Computational Biology program, Ms Pajau Vangay, in her study developed a predictive model with potential clinical importance for measuring healthy bacteria development in the gut of kids.
In further studies, the microbiome showed profound short- and long-term effects of antibiotics on the diversity and composition of the bacteria in our bodies.
"Related metabolic and immune system diseases are increasing dramatically, and in many cases we do not know why," said the senior author of this study, Mr Dan Knights, a computational biologist and assistant professor, Computer Science and Engineering Department, The Biotechnology Institute, University of Minnesota.
He further continued, "Previous studies showed links between both antibiotic use and unbalanced gut bacteria, and in others it showed links between unbalanced gut bacteria and adult disease. Over the past few years, we have synthesized hundreds of studies and found evidence of strong correlations between antibiotic uses, changes in gut bacteria and disease in adulthood."