Updated on 26 April 2015
Zaxine is a 'First-in-Class' treatment for HE that currently has limited options for long term treatment
Singapore: Lupin announced that its Canadian subsidiary, Lupin Pharma
Canada (collectively Lupin) has launched its first Brand product Zaxine, under a strategic licensing agreement with the North-Carolina-based GI specialty company Salix Pharmaceuticals.
Zaxine 550mg (rifaximin) is a long term antibiotic treatment for adults living with hepatic encephalopathy (HE), a complication of liver disease (cirrhosis).
The agreement grants Lupin exclusive rights to promote, distribute
and market Zaxine in the Canada.
HE can lead to a wide spectrum of mental and physical symptoms, including confusion, disruption in sleep patterns, personality changes and coma Zaxine 550mg has approved by Health Canada under priority review for the reduction in risk of overt HE recurrence in patients greater than or equal to 18 year of age.