Updated on 29 November 2013
Both companies will contribute to the collaboration, with 3M providing good laboratory practices (GLP) and good manufacturing practices (GMP) material for preclinical and clinical studies. The collaboration will evaluate the potency of 3M-051 conjugated to Ascend's proprietary oxidized mannan, which is part of its ASN-004 vaccine candidate and forms the basis of the ASN platform. These preclinical immunogenicity models will last up to 12 months. No further terms have been disclosed.
"3M is pleased to provide our TLR7/8 agonist 3M-051 to Ascend Biopharmaceuticals for use in combination with its cancer vaccines. The collaboration provides further validation of the utility of 3M's adjuvant portfolio," said James Ingebrand, President & General Manager at 3M Drug Delivery Systems.