Updated on 22 August 2013
So it is surmised that babies acquire the beneficial bacteria colonies while passing through the vaginal canal during normal delivery and this does not happen during C-section. Same is the case with two sets of beneficial chemicals, Th1 and Th2 in the blood, which are known to trigger immune responses in human body and organizes protection against many allergies early in human life.
The C-section infants had lower circulating levels of Th1 chemical messengers in their blood, indicating an imbalance between Th1 and Th2.
Dr Anders Andersson, KTH Royal Institute of Technology, Solna Sweden, and Professor Lars Engstrad, Karolinska Institute, Stockholm, Sweden, the co-authors of the research, said that, "Failure of Th2 silencing during maturation of the immune system may underlie development of Th2-mediated allergic disease."
The Swedish scientists pointed out that previous research has indicated that Bacteroides fragilis, one of the many Bacteroidetes, strongly influences the immune system, which ultimately enhances T cell activity and the Th1-Th2 balance."Thus, the lower abundance of Bacteroides among the C-section infants may be a contributing factor to the observed differences in the Th1-associated chemokines," they added.