ORIGIN is a step in this direction. It brings to light the possibility of preventing complications in diabetic patients through early insulin therapy."
"In patients with pre-diabetes or early type 2 diabetes and high CV risk, ORIGIN shows that it is possible to maintain low and stable HbA1c levels that are close to normal over a long time, and to potentially delay the progression from pre-diabetes to diabetes. Sanofi is proud to have sponsored this trial as a vital contribution to improving understanding of diabetes and the impact of long-term glycemic control," commented Riccardo Perfetti, MD, Vice President Medical Affairs, Global Diabetes, Sanofi.

"Our commitment to funding this vitally important long-term trial exemplifies our aim to help identify new ways of treating and understanding diabetes," commented Pierre Chancel, Senior Vice President, Global Diabetes, Sanofi. "I am pleased to announce that Sanofi will extend the observations of ORIGIN by an additional two years. All of these data will build on the extensive Lantus evidence in more than 47 million real-life patient-years and over 10 years of clinical experience involving 80,000 participants in clinical development programs."