Updated on 12 March 2014
Can you talk about the longevity of stem cells following their differentiation?
The extent to which a stem cell survives depends on a lot of things, including the processes involved to extract or transfer them. Usually cells that undergo cellular nuclear transfer can stay alive forever.
How do cells seek their position in the gradient? Do you believe in morphogenetic field theories?
It is a question of the ongoing concentration of cytoplasmic factors. These factors, which have a half-life of one hour, travel into the nucleus of the cell and lead to the binding of the promoter region of the gene. The concentration of these transcription factors determines the binding efficiency. However, the precise details are yet to be understood completely. Things like the dwell time of transcription factors are yet to be detmined.
What kind of hardships are scientists facing these days?
The difficulties and hurdles being faced by researchers stem cell or otherwise, have been similar across the world and across the ages. Getting financial support from organizations that provide grant is always tedious. You need to prove that the kind of research you are doing by utilizing the funds is worth it.
How does Sir John Gurdon define science?
Science is too complicated to be described by an individual.