Updated on 12 February 2013
Humanized mouse models enable scientists to develop human disease models and provide more predictive ways to test therapeutics for a variety of diseases. Through Taconic's Custom Model Generation Services, the experience gained in producing humanized mouse models is unparalleled. We have completed close to 200 humanization projects until date.
What are the various solutions that you provide to your customers?
Taconic's leading industry portfolio includes various solutions such as custom model generation services that provide easy access to precisely defined models to suit specific research project, using advanced technologies such as pronuclear microinjection, targeted gene mutation and targeted gene replacement; extensive animal model repositories, including the Taconic Transgenic Model portfolio of in-licensed transgenics; a Knockout Repository of more than 4,000 mouse lines; and an Emerging Models portfolio of investigator-sponsored models.
Our other solutions include tADMET models that yield far greater predictability of ADMET in man and improve the safety assessment of drug candidates by knocking out key murine genes or replacing them with their human counterparts; light-producing transgenic models that use novel bioluminescent technology to greatly enhance the study of inflammation, oncology, metabolic disease, and drug metabolism/toxicology; and custom breeding solutions that fit specific needs and are designed to help achieve research objectives by providing the right models quickly, cost-effectively and in the volume your research demands.
Furthermore, we provide surgical services, including cannulations and implants, customized procedures, and the creation of surgical models of disease, all performed by highly trained in-house surgical technicians; testing services that use the most advanced technology to determine the precise genetic characterization of your model and monitor animal health status; and health monitoring services through our proprietary Taconic International Health Monitoring System, which meets or exceeds the animal health guidelines of virtually all research institutions
What brings you to India and how do you plan to enter the Indian market?
I am in India this month to attend Bangalore India Bio 2013, LASA in Hyderabad and to announce an agreement with Vivo BioTech, which is located in Andhar Pradesh, to breed and distribute select Taconic rat and mouse models in India. Through this arrangement, the two companies will greatly improve the availability of high quality animals for biomedical research in India.