Updated on 26 March 2013
The big question – To collaborate or not to?
As the market for new drugs evolves, the methodologies for moving them into the market is changing and becoming more complex. Companies are increasingly relying on efficient collaboration strategies between the various parties involved in the entire value chain.
With the dawning of personalized medicine and the passing era of blockbuster molecules, pharmaceutical companies are slowly transforming from an industry of products to one of information. In addition, the shift to more integrated global operations, and a distributed organizational structure, make the reliance on effective collaboration tools of paramount importance. BioSpectrum takes a look at the top 10 collaborations that happened in the bioscience industry in India during 2012.
On February 21, 2012, Jubliant entered into drug discovery collaboration with Mnemosyne Pharmaceutical to identify preclinical candidates in the area of neuropsychiatric diseases. Dr Subir Basak, president, Jubilant Biosys, said, "The collaboration covers multiple programs, which are being enabled by Mnemosyne's expertise in drug discovery and NMDA receptor pharmacology and supported by Jubilant's translational center in Malvern, Pennsylvania and by scientists from Jubilant's India based facilities. The collaboration is integrating the capabilities of the companies across medicinal chemistry, NMDA receptor pharmacology, electrophysiology, computational chemistry and DMPK and in vivo pharmacology as appropriate in progressing promising compounds through preclinical development. Under the terms of the alliance agreement, Mnemosyne will exclusively own all IP generated and shall be responsible for clinical development and commercialization."
Dr. Reddy's -Merck Serono Partnership
Dr. Reddy's and Merck Serono partnered to co-develop a portfolio of biosimilar compounds in oncology, primarily focusing on monoclonal antibodies (Mabs) on June 6, 2012. Mr Karnvir Mundrey, director, Atharva Lifesciences Consulting said, "Biosimilars are next big thing for India after generics. Merck Serono's strength in developing, manufacturing and commercialization gives it an edge over its counter parts and Dr. Reddy's banks on its global expertise in marketing generics and biosimilars. Thus, it would be an obvious option for Merck Serono for a deal with Dr. Reddy's. Not to forget the cost savings for Merck Serono as phase-1 development is carried out by Dr. Reddy's. Also, to a fruitful extent, the agreement will be a mutual benefit for both the parties as R&D will be carried out on cost sharing basis, and commercialization will be done by both parties in US and Dr. Reddy's will receive royalties. Outside U.S with the exception of some markets where it will be co-exclusive and where Dr. Reddy's maintains exclusive rights. The deal will help Dr. Reddy's presence in the bio similars space in select emerging markets and enables participation globally."
Ranbaxy-Daiichi's Hybrid Business Model
Ranbaxy inked a deal on June 20, 2012 to launch hybrid business in Venezuela. This is a unique business model that Ranbaxy and Daiichi Sankyo started since the latter acquired Ranbaxy in 2008. This unique business model brings together the complementary strengths of a global generic company (Ranbaxy) and a top global innovator (Daiichi Sankyo). The coming together of the two entities marks a paradigm shift in how global pharmaceutical companies collaborate to serve the needs of patients effectively.