Singapore, April 18, 2008: US biotech firm Sigma-Aldrich has launched Imprint Chromatin Immunoprecipitation Kit for epigenetic research. According to Sigma, the Imprint ChIP Kit provides a complete solution for chromatin immunoprecipitation, including columns and reagents for DNA purification as well as an integrated protocol for ChIP DNA amplification with the GenomePlex, a whole genome amplification kit. This format allows for immunoprecipitation and purification of DNA from mammalian cells or tissue in a convenient microwell format.

 

The Imprint ChIP Kit is based on Chromatin Immunoprecipitation (ChIP) technology licensed from Epigentek Group. ChIP technology enables scientists to investigate complex DNA-protein interactions in vivo, potentially increasing the speed and accuracy of disease research and drug discovery. The Imprint ChIP Kit provides researchers with rapid and accurate results, enabling high-throughput, same-day downstream analyses via quantitative PCR, MS-PCR, and DNA sequencing as well as DNA microarray.

 

The Imprint ChIP Kit complements Sigma's product line to support the epigenetic workflow, including the Imprint DNA Modification Kit as well as products for DNA purification, qPCR, sequencing and post-reaction clean up.