Singapore, Mar 04, 2010: Biotage, a major supplier of tools and technology for medicinal and analytical chemistry, has announced further expansion of its family of products with the launch of Evolute WCX.

 

Evolute WCX is a mixed-mode weak cation exchanger, developed for extraction of strongly basic analytes and quaternary amines from aqueous samples. These analytes are typically found in pesticides and provide analytical scientists with the ability to extract pesticides from diverse matrices, ranging from ground water to blood samples.

The resin-based sorbent is surface modified with well defined hydroxyl-functional oligomers, imparting excellent water wettability. An optimized combination of non-polar (hydrophobic), polar (hydrophilic) and cation exchange interactions allows efficient extraction of strongly basic analytes of wide ranging polarities and quaternary amines, allowing for up to 50 percent more efficient recoveries of pesticide residues. The non-polar/cation exchange dual retention mechanism allows the use of a rigorous interference regime, providing extremely clean extracts and reducing matrix effects associated with LC-MS/MS analysis.

The announcement was made at the 2010 Pittcon in Orlando, Florida, the US.

“This is the second expansion of the Evolute family of resin-based, solid-phase extraction products, demonstrating our continued commitment to delivering high-quality solutions to our customers” said Mr Scott Carr, Vice President of Commercial Operations for Biotage.

Enhanced GO technology
Last week, the company had launched enhanced gradient optimization (GO) technology for its Isolera flash purification product line. According to the company, the GO technology can reduce solvent use and cost by 60 percent or more.

Sample purification is an indispensable tool for synthetic organic chemists. However, the costs associated with acquiring and disposing of solvents continues to increase. For many labs, the total solvent consumption used in purification work can be more than half of the lab’s yearly budget. “Biotage’s this new gradient optimization technology allows researchers to automatically convert less efficient linear gradients to an optimized step gradient with the press of a button” says Mr Bob Bickler, Senior Product Manager at Biotage.

 

Linear gradients typically use 13 or more column volumes of solvent but the Isolera GO feature can reduce the number of column volumes to seven or even five, reducing solvent use 60 percent or more.